Patent
Point of Care Detection of Hemoglobin
Abstract
The invention offers point-of-care detection of hemoglobin, including compositions, assays, kits, and devices. Specifically, it provides a liquid-based composition and assay for hemoglobin detection. Unlike solid-state readers, this assay doesn't require any solid support and utilizes more cost-effective sensors.
Uniqueness of the Solution
- Liquid-Based Paradigm: Introduces a unique liquid assay, departing from conventional solid-phase detection methods for hemoglobin.
- Hemoglobin's Pseudoperoxidase Activity: Utilizes a distinct mechanism, enhancing specificity and accuracy in detection.
- Versatile Deployment: Adaptable to diverse settings, from wet assays to dry reagent strips
- Integrated IoT Functionality: Unites with IoT technology for cloud-based analytics, a standout feature uncommon in hemoglobin detection devices.
- Liquid-Based Paradigm: Introduces a unique liquid assay, departing from conventional solid-phase detection methods for hemoglobin.
- Hemoglobin's Pseudoperoxidase Activity: Utilizes a distinct mechanism, enhancing specificity and accuracy in detection.
- Versatile Deployment: Adaptable to diverse settings, from wet assays to dry reagent strips
- Integrated IoT Functionality: Unites with IoT technology for cloud-based analytics, a standout feature uncommon in hemoglobin detection devices.
Current Status of Technology
- Current status: Liquid-based assay for hemoglobin detection without solid support, integrating IoT technology for cloud-based analytics.
- Output: Rapid and accurate determination of hemoglobin concentration, with sensitivity of 65% and specificity of 93% with detected value of 0.4 gm/dl of hemoglobin.
- Advantages: Cost-effective, versatile deployment in wet and dry phase assays, interference-free with substances like uric acid and glucose.
- Prototype Features: Utilizes LED and sensor technology (TSL2591 or AS7276), with an integrated electronic reader for easy and efficient testing.
- Comparative Edge: Offers stability, affordability, and enhanced accuracy compared to existing products, with features like real-time data tracking and long battery life.
Technology readiness level
3
Societal Impact
- Improved Healthcare Access: Enhances access to timely hemoglobin testing, improving healthcare facility.
- Environmental Protection: Facilitates early detection of hemoglobin contamination in water sources, safeguarding public health and environmental integrity.
Relevant Industries, Domains and Applications
Healthcare diagnostics, biotechnology, medical device manufacturing, point of care testing industry.
Applications or Domain
- Medical Diagnostics: Revolutionizes point-of-care hemoglobin testing, facilitating rapid and cost-effective screening in healthcare facilities.
- Biotechnology: Enables hemoglobin detection in research laboratories, aiding in studies related to blood disorders and diseases.
- Pharmaceutical Manufacturing: Streamlines quality control processes by providing a reliable method for hemoglobin assessment during drug development.
- Environmental Monitoring: Supports environmental agencies in assessing water quality by detecting hemoglobin contamination in aquatic ecosystems.
Application Number
202121011784
Filing Date
Grant Number
434170
Grant Date
Assignee(s)
Indian Institute of Technology Bombay