3D nano-hydroxyapatite/gelatin/carboxymethyl chitin composite engineered with controllable viscoelastic properties for guided bone regeneration
This invention relates to three-dimensional nano-hydroxyapatite/carboxymethyl chitin/gelatin scaffold construct for guided bone regeneration and a process to manufacture the same. The present scaffold construct has efficient mechanical as well as controllable visco-elasticity in body milieu or wet condition, hemocompatibility, biocompatiblility.
A method of preparation of ultra-small polymeric nanoparticle
The invention relates to a method of preparation of ultra-small polymeric nanoparticles as carriers for pharmaceutically active agents, the polymeric nanoparticles having size 100nm or less, preferably 50nm or less with high surface to volume ratio. The method does not employ excipients like stabilizers, surfactants, emulsifiers, etc, thereby avoiding the steps of purification of nanoparticles.
Key words: Cancer, Theranostic
A method and a system for producing thermolabile nanoparticles with controlled properties and nanoparticles matrices made thereby
This invention relates to a single-step, continuous method and a system for processing thermolabile biomaterials, like lipids and biopolymers, and heat-sensitive drug molecules, into nanoparticles with controlled properties. The method enables control over time-temperature history to influence aerosol dynamics and achieve minimal thermal damage to matrix materials or encapsulated agents.