This patent presents a method for synthesizing water-soluble WS2 quantum dots, addressing the challenge of poor solubility of WS2 in aqueous environments. By dispersing WS2 powder in water with PEG followed by sonication and hydrothermal heating, the invention achieves WS2 quantum dots with enhanced dispersibility and biocompatibility, crucial for biomedical applications.
Figure (1) (a-c) Transmission Electron microscope images (d) High resolution image (e) Diffraction Pattern and (f) The energy dispersive X-ray spectroscopy of PEG_WS2Quantum Dots
Current methods for synthesizing WS2 quantum dots (QDs) using organic solvents result in poor solubility, limiting their biological applications.
- PEG as a Surfactant: PEG plays a dual role by dispersing WS2 and preventing aggregation during synthesis.
- Sonication and Hydrothermal Heating: These processes ensure uniform size and morphology of WS2 quantum dots, critical for consistent optical and biomedical performance.
Water Solubility: Achieved through careful control of PEG to WS2 ratio, ensuring stable aqueous dispersion suitable for biomedical applications.
Advantages of the technology:
- Biocompatibility: WS2 quantum dots synthesized using this method exhibit low cytotoxicity and good cell permeability, crucial for biomedical applications.
- Scalability: Green synthesis approach allows for large-scale production of uniform WS2 quantum dots suitable for industrial applications.
- Optical Properties: Enhanced fluorescence and photoluminescence properties make WS2 quantum dots ideal for optical and sensing applications.
- Uniformity: WS2 quantum dots with a diameter of approximately 3.10±0.72 nm, characterized by TEM and high-resolution imaging techniques.
- Crystallinity: Structural analysis confirming crystalline nature and stability of quantum dots in aqueous environments.
- Performance: Optical and fluorescence properties suitable for various biomedical and optoelectronic applications, validated through experimental setups and characterization techniques.
The technology is patented.
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Enables safer and more effective biomedical applications of WS2 quantum dots due to improved solubility and biocompatibility.
- Biomedical Imaging: WS2 quantum dots can serve as fluorescent probes for cellular and tissue imaging.
- Therapeutics: Potential in photothermal therapy and drug delivery due to their biocompatibility and photoresponsive properties.
- Sensor Technology: Utilization in high-sensitivity sensors for environmental monitoring and medical diagnostics.
Geography of IP
Type of IP
202021037515
432989