This invention presents a novel and efficient process for synthesizing 6-deoxy-L-idoside from L-Rhamnose. The process involves a series of regioselective protections, triflation, and nucleophilic displacement reactions to transform L-rhamnose into valuable 6-deoxy-L-sugar derivatives like 6-deoxy-L-idoside.
The commercial availability of 6-deoxy-L-sugars is limited, with only L-rhamnose and L-fucose readily accessible. The current methods for synthesizing rare sugars like 6-deoxy-L-idoside are complex, inefficient, and involve multiple protection and deprotection steps, resulting in low yields and high production costs.
- Regioselective protection of hydroxyl groups in L-Rhamnose
- Triflation and nitrite anion-mediated inversion techniques
- Cascade inversions for the synthesis of 6-deoxy-L-hexoses
- Streamlined synthesis process for 6-deoxy-L-hexoses
- Utilizes inexpensive and readily available L-rhamnose
- Improves overall yield and efficiency compared to existing methods
- Cost-effective production suitable for industrial applications
The prototype involves a step-by-step synthesis process starting from L-Rhamnose, employing selective protection, triflation, and inversion reactions to produce 6-deoxy-L-idoside in higher yields.
The process has been successfully developed and demonstrated at the laboratory scale, with potential for scaling up for industrial production.
This technology reduces production costs and increases the availability of rare sugars, leading to more affordable pharmaceuticals, and greatly impacting the biotechnology industries, thereby improving public health and contributing to economic growth.
- Pharmaceutical industry for the synthesis of glycopeptides and antibiotics
- Biotechnology for producing oligosaccharides and terpene glycosides
- Food and nutrition
- Chemical manufacturing
- Research and development in organic chemistry and carbohydrate synthesis
Geography of IP
Type of IP
202122003638
394313