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Industrial Research And Consultancy Centre
Patent
A Microfluidic Device for Separating Platelets from a Blood Sample
Abstract

The invention is a microfluidic device designed to separate platelet-rich plasma (PRP) and platelet-poor plasma (PPP) from blood. It uses a single-layer microdevice to exploit biophysical and geometrical effects for efficient separation of plasma with varying platelet concentration, providing high purity PRP and PPP suitable for medical and research applications.

Societal Impact
  • Enhanced Medical Procedures: Provides a reliable source of high purity PPP and PRP for various medical treatments, improving patient outcomes. 
  • Cost Reduction: Simplified fabrication and operation reduce costs in clinical and research settings
Salient technical features and Advantages of the Technology
  • High Purity: Achieves high purity PRP and PPP with minimal manual intervention due to the inclusion of Single-Layer Microchannel: Simplifies the design and fabrication 
  • Cost-Effective and Easy Fabrication: Single-layer design is simpler and cheaper to produce. 
  • No External Sources Required: Operates without needing additional equipment by the peculiar design that involves 
  • Minimal Contamination Risk: Reduces manual handling, thus lowering contamination risks.


Technology readiness level

3

Current Status of Technology

At present the prototype that has been produced has been tested at various flow rates, the device effectively separated PPP and PRP with high purity, demonstrating its practical applicability.

Relevant Industries

Medical Diagnostics, Pharmaceuticals, Regenerative Medicine

Applications or Domain
  • Medical Diagnostics: Used for preparing PRP and PPP for platelet aggregation studies, tissue regeneration, and other medical applications 
  • Surgical Applications: PPP acts as a fibrin glue for hemostasis and tissue adhesion, reducing postoperative complications. 
  • PRP is used for wound healing and recovery Biomedical Research: Useful in studying blood components and related physiological processes
**This IP is jointly owned**