The invention offers point-of-care detection of hemoglobin, including compositions, assays, kits, and devices. Specifically, it provides a liquid-based composition and assay for hemoglobin detection. Unlike solid-state readers, this assay doesn't require any solid support and utilizes more cost-effective sensors.
Figure 1. Hemoglobin device
Current hemoglobin detection methods often rely on expensive solid-state readers, limiting accessibility in point-of-care settings. This invention addresses this issue by introducing a liquid-based assay that eliminates the need for solid support, offering a more affordable and accessible detection solution.
- Liquid-Based Paradigm: This technology introduces a unique liquid assay, departing from conventional solid-phase detection methods for hemoglobin.
- Hemoglobin's Pseudoperoxidase Activity: It utilizes a distinct mechanism, enhancing specificity and accuracy in detection.
- Versatile Deployment: It is adaptable to diverse settings, from wet assays to dry reagent strips.
- Integrated IoT Functionality: It unites with IoT technology for cloud-based analytics, a standout feature uncommon in hemoglobin detection devices.
The prototype utilizes LED and sensor technology (TSL2591 or AS7276), with an integrated electronic reader for easy and efficient testing.
This technology uses a liquid-based assay for hemoglobin detection, without solid support, and integrates IoT technology for cloud-based analytics. It demonstrates rapid and accurate determination of hemoglobin concentration, with sensitivity of 65% and specificity of 93% with detected value of 0.4 gm/dl of hemoglobin.
This technology is cost-effective, versatile deployment in wet and dry phase assays, interference-free with substances like uric acid and glucose. It offers stability, affordability, and enhanced accuracy compared to existing products, with features like real-time data tracking and long battery life.
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This technology enhances access to timely hemoglobin testing, improving healthcare facility. It also facilitates early detection of hemoglobin contamination in water sources, safeguarding public health and environmental integrity.
- Point-of-Care Medical Diagnostics: Revolutionizes point-of-care hemoglobin testing, facilitating rapid and cost-effective screening in healthcare facilities
- Biotechnology: Enables hemoglobin detection in research laboratories, aiding in studies related to blood disorders and diseases
- Pharmaceutical Manufacturing: Streamlines quality control processes by providing a reliable method for hemoglobin assessment during drug development
- Environmental Monitoring: Supports environmental agencies in assessing water quality by detecting hemoglobin contamination in aquatic ecosystems
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