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Industrial Research And Consultancy Centre
Patent
Lycopene Based Compositions for Sunburn and Cosmetic Applications and Preparation Method Thereof
Abstract

This product is a topical cream for treatment of burn or other cosmetic purpose like anti-aging, anti-inflammatory, antibacterial and antioxidant properties. It includes carbopol gel combined with lycopene nanosuspension and liposomes containing diclofenac diethylamine. The lycopene nanosuspension is made up of lycopene, a surfactant, a solvent, and a humectant. The cream has a pH level between 5 to 6. It's designed to be used for various skin conditions like burns and has additional benefits like reducing signs of aging, fighting inflammation and bacteria, and providing antioxidant effects.

Figure 1. SEM micrographs of (A) and (B) Liposomes, (C) Carbopol gel, (D) Lycopene loaded carbopol gel, and (E) and (F) Composite gel revealing the internal structure and organisation of the gel matrix

Problem Statement

Existing topical treatments for skin conditions often lack a comprehensive approach, with limited effectiveness against multiple skin issues. There is a need for an advanced topical composition that addresses various skin concerns, offers enhanced therapeutic benefits, and ensures safety in application.

Uniqueness of the Solution
  • Skin Burn Treatment: This technology has novel topical composition for skin burn treatment. It addresses multiple aspects of burn care in a single formulation. 
  • Lycopene Nanosuspension: It combines lycopene nanosuspension with diclofenac-loaded liposomes. Lycopene's antioxidant properties aid UV-induced damage prevention and liposomes enhance diclofenac delivery for pain relief. 
  • Suitable for Skin: The pH of the composition is optimized for skin compatibility. The process ensures homogenous dispersion and stable pH. 
  • Liposomal Encapsulation: It enhances skin penetration due to liposomal encapsulation. It has potential to revolutionize burn management with improved efficacy.
Prototype Details

The topical composition effectively treats skin burns, offering significant anti-inflammatory and antioxidant benefits.

Current Status of Technology

The technology is in the advanced formulation stage, focusing on combining lycopene nanosuspension and diclofenac-loaded liposomes in a Carbopol gel. 

Technology readiness level

2

Societal Impact

This technology reduces pain and enables faster healing for burn victims, enhancing their quality of life. Healthcare costs associated with burn treatment are lowered due to decreased hospital stays and outpatient care. It empowers individuals and communities with effective, accessible burn care solutions, potentially saving lives in emergencies.

Applications or Domain
  • Hospitals and Pharmaceuticals: Clinical use in hospitals and burn care centers 
  • Cosmetics and Skincare: For soothing and healing minor burns, enhancing skincare products' efficacy

Geography of IP

Type of IP

Application Number

202121029916

Filing Date
Grant Number

523564

Grant Date
Assignee(s)
Indian Institute of Technology Bombay
**This IP is owned by IIT Bombay**