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Industrial Research And Consultancy Centre

Protein crystallography facility

X-ray crystallography technique helps to determine biological macromolecule structures that provide a detailed understanding of the interactions occurring at the molecular levels. Structure based drug design, study of protein-ligand interactions and structure-function relationships are the major fields where X-ray crystallography acts as a major tool.
Make and Model
Detector : Rigaku, R-Axis IV++
Available mode for use
Screen protein and DNA/RNA crystals for preliminary diffraction to improve quality Solve structure of know protein structures with ligands (molecular replacement) (inhibitors, substrates, nucleic acids etc.) Solve structure of new bio-molecules by using heavy atom derivatization (Hg, lanthanides etc.) (isomorphous replacement) Fibre diffraction of bio-fibres (amyloids). Difficult small molecule structure, source is Cu Kα

X-Ray diffraction Automated crystallization set up facility Automate crystal visualization camera

  • Crystal structure determination of proteins and their complexes by molecular replacement method
  • Crystal structure determination of proteins by heavy atom isomorphous replacement


Faculty in-charge
Contact Email

Room No. 103, Ground floor, Sophisticated Analytical Instrument Facility (S.A.I.F), I.I.T. Bombay, Powai, Mumbai - 400 076.

Other Contact Person
  • Prof. Ruchi Anand
  • Prof. Prasenjit Bhaumik