This invention presents a novel and efficient process for synthesizing 6-deoxy-L-alloside starting from L-rhamnose. The process involves a series of regioselective protections, triflation, and nucleophilic displacement reactions to transform L-rhamnose into valuable 6-deoxy-L-sugar derivatives like 6-deoxy-L-alloside.
Type of IP
Faculty
Category of Patent
Department
This technology reduces production costs and increases the availability of rare sugars, leading to more affordable pharmaceuticals, and greatly impacting the biotechnology industries, thereby improving public health and contributing to economic growth.
- Regioselective protection of hydroxyl groups in L-Rhamnose
- Triflation and nitrite anion-mediated inversion techniques
- Cascade inversions for the synthesis of 6-deoxy-L-hexoses
- Streamlined synthesis process for 6-deoxy-L-hexoses
- Utilizes inexpensive and readily available L-rhamnose
- Improves overall yield and efficiency compared to existing methods
- Cost-effective production suitable for industrial applications
4
The process has been successfully developed and demonstrated at the laboratory scale, with potential for scaling up for industrial production.
Pharmaceutical Industry, Biotechnology Firms, Chemical Manufacturing, Agricultural Biotechnology
- Synthesis of components for antibiotics, antitumor agents, and glycopeptides.
- Production of biologically active glycosides used in various therapeutic treatments.
- Development of new chemical pathways for sugar derivatives.
- Potential use in the synthesis of bioactive compounds for plant protection and growth.